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A bacteria that causes gum disease has been linked to Alzheimer’s disease in a study scientists believe could pave the way for new treatments targeting the debilitating condition. An enzyme called gingipains, which the Porphyromonas gingivalis (P. "main cause of Alzheimer’s disease," Dr.ada.org Steve Dominy, study author and associate professor at University of California, told Newsweek. However, other experts in the field responded cautiously to the findings published in the journal Science Advances.youtube.com Researchers first compared the brain tissue of patients with and without Alzheimer’s disease. They found 96 percent of 53 patients with the condition had RgpB, or a form of the gingipains enzyme known as arginine-gingipain. And 91 percent of 54 patients tested positive for Kgp, or lysine-gingipain. These were detected at levels significantly higher than the control samples, the authors said.


DNA tests on three brains with Alzheimer’s disease and six healthy brains also had the gene associated with P. gingivalis in their tissue. The team also examined the cerebrospinal fluid and saliva of 10 patients believed to have Alzheimer’s disease, and found the P. gingivalis gene hmuY in seven, and P. gingivalis itself in all of them. And in an experiment on mice, those dosed with gingipains had higher levels of the hallmark Alzheimer’s protein, amyloid beta, and greater damage to their neurons than those who didn’t. What’s more, when mice were treated with a drug blocking the enzymes, the neurodegeneration stopped.


Around half of adults have periodontitis. Some 10 percent experience a severe version of the disease, which erodes the gums and the bones that keep our teeth in place, the authors said. The researchers hope a drug that inhibits the spread of P. gingivalis in the brain could slow the symptoms of the neurodegenerative disorder. "In addition, our finding of DNA from P. gingivalis in the cerebrospinal fluid of living AD patients provides further evidence that P. gingivalis infects the central nervous system. Based on these findings, we believe that P. gingivalis is the main cause of Alzheimer’s disease, and the gingipains are the main drivers of Alzheimer’s disease pathology. "These findings provide a new strategy for Alzheimer’s treatment by specifically targeting P. gingivalis and gingipains instead of amyloid beta," he said.


However, he said the study was limited because the team has not yet determined if different strains of P. gingivalis are more virulent than others in causing brain infection. "This remains an area of active investigation," he said. Those concerned that poor dental health could increase their risk of Alzheimer’s disease are advised to practice good oral hygiene to preclude the prevalence of P. gingivalis in the mouth, said Dominy. But he stressed this won't prevent the brain from becoming infected by P. gingivalis. However, he welcomed the avenue of inquiry as no new drugs targeting Alzheimer’s have been released for over 15 years. "It’s important we carefully assess all new potential treatments, and this drug is currently in an early phase clinical trial to establish if it is safe for people.


This would result to deep folds at the corner of the mouth and thinning of the lips and this can easily age the appearance of most individuals. This is why the service of dental implant in Markham is needed to resolve the problem. The collapse of facial structure: - Once many back teeth are lost, it would result to the loss of facial support of the cheek and cause sunken look as well as a premature aging. Loss of Bone: - The support of our tooth root is the natural purpose of our upper and lower jaw bones. Once the roots are lost, the bone would begin to melt away just like an unused muscle.wikipedia.org This would result to a further loss of facial support and may make it impossible to wear an artificial prosthetic. It can also make it difficult to have dental implant in Markham because it will give dentists in Richmond hills a lot of challenges.


I was at the dentist recently for a toothache. He snapped some X-rays, gave my mouth a quick lookover, said I appeared to have cracked the tooth (likely from my severe TMJ) and would need a root canal. He forwarded me to an endodontist. The endodontist discovered I had a strange mass in my jaw that appeared unrelated to the cracked tooth. He put me on antibiotics to prevent infection and forwarded me to an oral surgeon, who confirmed the mass was harmless. Now I’m going back to the endodontist for the root canal, and then back to the dentist for the crown. 500 and about eight hours in dental chairs to get this far. It will be thousands more dollars and dozens more hours before I solve this problem.


None of it is covered by medical insurance. I should have gotten dental insurance, right? That’s what I kept telling myself, until I actually looked into the dental plans for which I qualify (more on that in a moment). But the real question here: Why is dental not covered under medical insurance? The same may be asked of vision, but at least there if you have a serious eye problem (like glaucoma or cataracts) you go to an ophthalmologist, which is covered by medical. Such isn’t the case with dental. The oral cavity is a gateway to your body. The partition between dental and medical makes little sense given that "oral health is directly related to general health," says Dr. Gary Glassman, an endodontist based in Toronto, Canada who also practices in the U.S.


"The oral cavity is a gateway to your body. Despite it being a plainly medical issue, oral health has always been an outlier. Until the 1800s, dentistry was the domain of barbershops, practiced in the same chair and usually by the same guy who shaved your beard. "How would you feel if you went to your hairdresser and they pulled your tooth or lanced your abscess? " asks Dr. Glassman. It’s so bizarre and frightful an image that it’s almost comical, but the history of our teeth and jaws being treated as something as incidental as our hair and nails still haunts us. "Dentistry has always had a disconnect to medicine," says Dr. Michael Tischler who specializes in reconstructive dentistry and the implant editor for Dentistry Today. Why isn’t a health problem so serious it can be deadly, not considered medical?


To an extent, it’s because it’s not that common to end up in the hospital as a result of a tooth or gum problem — not if you’re keeping up with preventative dental care. Provider Syndicate, a management advisory and operational consulting firm focused on the managed care and healthcare delivery industries. "If you’re having a heart attack you'll go to the ER right away. Dental problems can often wait and unfortunately often do. Yes, dental problems often do wait. Mine is waiting until my next paycheck (or three).yelp.com But the argument that dental problems are less severe than "medical" ones doesn’t quite hold up, not when you look at the numbers of ER visits for which dental-related problems account. "More than 800,000 annual ER visits arise from preventable dental problems," says Dr. Allena Willis Kennerly, an orthodontist. Now, let’s say you do have dental insurance.


That’s certainly more favorable than the alternative, but it’s hardly ideal. If you undergo a serious procedure, you’ll likely still be left with a hefty bill. "Dental insurance, unlike medical, is not regulated and it tends to be very constrained," says Powell. And it’s a relatively new type of insurance, with Dr. Bobbi Stanley, a dentist, noting that it was first introduced some 60 years ago. "Dental work was a fee for service agreement until the mid-50’s when dental insurance was introduced in California," says Dr. Stanley. Inflation may have catapulted the worth of the dollar over the decades, but the reimbursement rate for dental insurance hasn’t budged much.wikipedia.org 1,500.00," says Dr. Anil Dwivedi, a general dentist with a specialty in anesthesiology. Clearly the purpose of dental insurance is not to cover dire issues, but to prevent them — by encouraging regular maintenance.


A few oil changes can go a long way (to stick with Powell’s disturbingly apt analogy), and preventative care does have a terrifically positive impact on one’s oral health. But it doesn’t prevent every problem. Take me for example. 600 bite guard at night (which was made for me by a dentist when I had dental insurance, and which was not covered by my dental insurance). Problems like mine are, evidently, not so rare. "Unfortunately we see extreme situations like this all the time," says Dr. Tischler. "So even though I preach prevention, prevention, prevention, it won't save you from serious dental emergencies.


And that is compounded by the fact that while dental insurance will cover preventative aspects of dental care it doesn’t always cover major dental procedures for adults. Dr. Powell asserts that one major reason dental plans tend to be so minimal in what they cover, is because people don’t want to shell out higher premiums. ] were more inclusive, that could be a problem because then premiums would be higher, and if premiums were higher, plans would be less appealing to people," says Powell. "I buy the dental plan because it’s a good rate and it’s cheaper than paying directly out of pocket.


There are still a lot of people not buying dental insurance, even when many plans costs less than a Netflix subscription. No judgments, people, I’m in the same camp. "Some 74 million Americans had no dental coverage in 2016," says Dr. Tischler.youtube.com "The dentally uninsured rate has increased to about four times the medically uninsured rate — even with dental coverage expansions. In part, this is due to the lack of dental coverage in traditional Medicare. Dentists are trying to decrease the separation between dentistry and medicine because we are doctors of oral medicine. It doesn't look like interest in dental insurance will pick up in 2017, but someday we might not have to worry about it. There is a glimmer of hope that dental will eventually be covered under medical in the future.


"It's widely accepted that dental and medical are separate, but the gap is closing as we move forward," says Glassman. There’s also the mounting data that the healthcare industry could benefit from covering dental as part of medical. Consider those 800,000 ER visits per year for dental-related problems. Wouldn’t more people get the preventative dental care if it were covered by their medical insurance? Couldn’t medical insurance companies ultimately save oodles of money on emergency care if the problem were nipped in the bud free of charge? Dr. Glassman certainly thinks so. "It would be more affordable for medical insurance to include basic dentistry," says Dr. Glassman. Want more tips like these? NBC News BETTER is obsessed with finding easier, healthier and smarter ways to live. Sign up for our newsletter and follow us on Facebook, Twitter and Instagram.


Invisalign treatment uses a series of clear, removable aligners that slowly work to straighten your teeth and align your bite. Invisalign aligners are more comfortable and provide a better fit than aligners made from off-the-shelf material. Appointment times can be shorter with Invisalign treatment, and patients can go up to 12 weeks between appointments providing you more convenience for your busy life. As a Diamond Plus provider of Invisalign aligners, Orthodontic Associates is among the top practices in the United States and Canada who have treated the highest number of patients. We pride ourselves in taking the difficult and challenging Invisalign treatment cases and turning them into success stories for adults and teens across the Oklahoma City and Edmond, OK areas.


Listen to Dr. Amy discuss the techniques and benefits of Invisalign treatment. Contact our office today at either our Oklahoma City or Edmond offices to schedule your free consultation for yourself or your teen. We are ranked as a Diamond Plus provider of Invisalign clear aligners, which means we are among the top orthodontists in the United States and Canada who have treated the highest number of patients. We have treated over 2,000 Invisalign patients total, which is the most in the state of Oklahoma. Dr. Brian Amy serves as an international speaker and faculty member for Align Technology, Inc, the maker of the Invisalign clear aligner system. Each year, Dr. Amy speaks to hundreds of orthodontists from around the world to educate, mentor and advocate for the Invisalign treatment options available for adults and teens. Dr. Brian Amy has participated in multiple research studies that have resulted in national journal publications and advances in Invisalign treatment.


Houston dental implants dentist, Wayne Brueggen, DDS, has been caring for the dental implant needs of his patients for over 35 years. His dental implant solutions offer simple, reliable and long-lasting results for patients of any age who are missing teeth or experiencing the frustrations of loose, decayed and broken teeth. Dr. Brueggen has extensive experience with the amazing All-on-4® dental implant procedure. In one day, patients can leave his office with a new, natural-looking smile that feels like permanent teeth, works like permanent teeth, is cared for like permanent teeth and may last even longer. There is virtually no downtime.


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